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An anti-aging drug for dogs is in the works: Here's what we know

Published Sat, 22 Feb 2025 10:25:33 GMT

(NewsNation) — In a significant step toward potentially extending the lifespan of large- and giant-breed dogs, a San Francisco-based company, Loyal, received conditional approval from the Food and Drug Administration (FDA) for its drug called LOY-001. The drug, designed to address the shorter lifespans of larger breeds, is anticipated to hit the market as early as 2026, pending FDA approval of Loyal's manufacturing and safety data.  “Loyal was founded with the ambitious goal of developing the first drugs to extend healthy lifespan in dogs,” said Loyal CEO Celine Halioua. “This milestone is the result of years of careful work by the team. We’ll continue to work just as diligently to bring this and our other longevity programs through to FDA approval.”  Border and immigration: Where Republican candidates stand Large- and giant-breed dogs often face lifespans that are significantly shorter than their smaller counterparts, with breeds like Great Danes and Newf...

They're in: Texas makes College Football Playoff, will play No. 2 Washington in Sugar Bowl

Published Sat, 22 Feb 2025 10:25:33 GMT

AUSTIN (KXAN) — The Texas Longhorns are in the College Football Playoff for the first time in program history.No. 3 Texas will play No. 2 Washington in the Sugar Bowl at 7:45 p.m. CT, Jan. 1, 2024. No. 1 Michigan will play No. 4 Alabama in the Rose Bowl at 4 p.m. CT, Jan. 1, 2024. The CFP National Championship game will feature the winners of those games on Jan. 8 at NRG Stadium in Houston.MORE THAN THE SCORE: Stay up to date on sports stories like these, and sign up for our More than the Score sports newsletter at kxan.com/newsletters"I feel good," Longhorns head coach Steve Sarkisian said. "I've always said if we get in, we can play with anybody in the country. Our versatility stacks up against just about anybody."Florida State is the first undefeated champion from a Power 5 Conference that wasn't selected to the playoff. The committee ranked them No. 5 and the Georgia Bulldogs at No. 6. Alabama defeated Georgia 27-24 to win the SEC championship Saturday, and even though Florida S...

A bit colder Monday after an early morning cold front

Published Sat, 22 Feb 2025 10:25:33 GMT

AUSTIN (KXAN) -- Warmer winds from the southwest helped push temperatures into the lower and middle 70s Sunday, even with plenty of high clouds around.Those clouds will continue to shift eastward as we head through this evening.Early Monday morning a dry cold front drops through Central Texas bringing a cooler wind shift and knocking temperatures down a little bit.Overnight lows drop into the mid 40s under a mostly clear sky.We'll have abundant sunshine on Monday with highs in the upper 60s making for a very pleasant afternoon.Expected highs on MondayTemperatures warm back closer to 70º beginning Tuesday and Austin may stay in the 70s the rest of the work week and into next weekend.Highs the next few daysRain chances aren't very high next weekend, but we'll have 20% chances for both days. A stronger cold front looks to drop in to knock temperatures down below average on Sunday. Winter Weather Outlook: What a strong El Niño could mean for rainfall and ice risk Austin Interactive...

Wild jump on Chicago early, remain unbeaten under new coach John Hynes

Published Sat, 22 Feb 2025 10:25:33 GMT

The Wild remained perfect under new head coach John Hynes with a 4-1 victory over the Chicago Blackhawks on Sunday at Xcel Energy Center.Marco Rossi scored two goals, and Marc-Andre Fleury stopped 27 shots to earn his 548th NHL victory and move to three wins from tying Patrick Roy for third all time.Mats Zuccarello added a goal and two assists, and Matt Boldy scored one of two power-play goals for Minnesota, which is 3-0 since Hynes succeeded Dean Evason before a 3-1 victory over St. Louis last Tuesday at the X.Rossi scored twice in the first period, first when he deflected a wrist shot by Faber past Petr Mazrek 2 minutes, 11 seconds into the game. He gave the Wild a 2-0 lead with his power-play goal at 12:08, a one-timer from the slot on a pass from Freddy Gaudreau.Brock Faber had assists on both goals, including his first as part of the Wild’s second power-play unit.Mats Zuccarello put the Wild up 3-0 late in the first period, whacking in a one-timer from the right circle from a p...

Gophers will play Bowling Green in the Quick Lane Bowl in Detroit

Published Sat, 22 Feb 2025 10:25:33 GMT

The Gophers football team will head to a familiar bowl game against a recognizable opponent that conjures a hurtful memory.Minnesota (5-7) will play Bowling Green (7-5) in the Quick Lane Bowl at Ford Field in Detroit at 1 p.m. on Dec. 26.The Gophers will be making their third overall appearance in the Quick Lane Bowl; they went to the Detroit Lions’ home stadium as a 5-7 team in 2015 and beat Central Michigan 21-14. Then as a 6-6 squad in 2018, they beat Georgia Tech 34-10.This matchup will harken to Minnesota’s most-surprising loss under head coach P.J. Fleck. The Gophers were 31-point favorites before losing at home to Bowling Green 14-10 in 2021. It was the second-largest Big Ten upset in at least the past 40 years, following Minnesota losing to Northwestern in 1982 despite being a 31.5-point favorite going into the game.The majority of national bowl projections earlier this week had the Gophers going to the Quick Lane Bowl, but that picture seemed to shift Saturday n...

Motorist killed in St. Paul crash, 2 injured following brief State Patrol pursuit on I-94

Published Sat, 22 Feb 2025 10:25:33 GMT

A female motorist was killed and two others in her vehicle were injured early Sunday following a brief chase on Interstate 94, the State Patrol said.A trooper saw the vehicle moving rapidly on eastbound I-94 near Hamline Avenue just before 2 a.m. An attempt to halt the vehicle with emergency lights and sirens near Dale Street failed, according to an incident report.The trooper aborted the pursuit as the driver attempted to exit at Marion Street. The vehicle careened through an intersection and slammed into a concrete wall, the report said.The driver was killed.Two passengers were taken to Regions Hospital in St. Paul. A 41-year-old man has life-threatening injuries, according to the report, and a female has non-life-threatening injuries.It was not clear whether any of the victims were wearing seatbelts. The accident triggered an airbag deployment, but it was unclear from the report where and how many of the bags in the vehicle activated.SAINT PAUL: A driver who was apparently fleein...

Mizzou selected for Cotton Bowl against Ohio State

Published Sat, 22 Feb 2025 10:25:33 GMT

COLUMBIA, Mo. — No. 9 Missouri will face No. 7 Ohio State in the Cotton Bowl on Friday, December 29.Kickoff is set for 7 p.m. at AT&T Stadium in Arlington, Texas. This is Mizzou's first New Year's 6 bowl game under head coach Eli Drinkwitz in his first double-digit win season. It's also Mizzou's first NY6 Bowl since 2013 when they faced Oklahoma State in that year's Cotton Bowl, the year before the four-team College Football Playoff format was instituted. Additionally, this marks the Tigers' third straight bowl game under Drinkwitz in his four seasons at command in Columbia. At 10-2, Mizzou finished second in the SEC East. Similarly, the 11-1 Buckeyes finished second in the Big Ten East.

These are the best public colleges, universities in Missouri

Published Sat, 22 Feb 2025 10:25:33 GMT

If you're going to go to college — or send your child to college — you want to choose the best one. But what exactly that means is different for each person. There are a lot of factors, including how big the college is both overall and in terms of class sizes. It also matters whether a college has good programs for the fields you're more interested in studying, the types of sports or other student activities that interest you, decent access to student housing either on or off campus, and a high graduation rate. Two Kansas City-area schools named 2023 National Blue Ribbon Schools There's also life after college to consider: Does a college have a good support system for people seeking employment, a strong alumni network, or a high rate of job placements at or just after graduation?Colleges themselves suggest the most important factors for students are, or should be, emotional ones, like "whether you feel comfortable on campus," as the University of South Florida puts it, or "h...

PHOTOS: Denver Broncos fall to Houston Texans 22-17 in NFL Week 13

Published Sat, 22 Feb 2025 10:25:33 GMT

The Denver Broncos faced the Houston Texans at NRG Stadium in Houston on Sunday, Dec. 3, 2023. Denver fell short on a late comeback attempt, losing 22-17. Denver falls to 6-6 on the season and had its five-game winning streak snapped.Related ArticlesDenver Broncos | Broncos four downs: Russell Wilson’s three interceptions end Team Takeaway’s five-game win streak Denver Broncos | How it Happened: Broncos’ five-game winning streak comes to an end with loss to Texans Denver Broncos | Broncos elevating QB Ben DiNucci, TE Lucas Krull from practice squad and activating WR Brandon Johnson from IR Denver Broncos | Broncos Journal: RT Mike McGlinchey using cleats to honor late cousin Dan McCain, “my best friend and biggest supporter” Denver Broncos | Broncos prepare for Texans QB C.J. Stroud: “It’s unusual what he’s accomplishing as a rookie”

Heroes and Zeros from Broncos’ loss to Texans: Alex Singleton’s costly penalty proves critical in close game

Published Sat, 22 Feb 2025 10:25:33 GMT

Here are the heroes and zeros from the Broncos’ 22-17 loss to the Houston Texans on Sunday afternoon at NRG Stadium.HeroesDenver’s situational defense: It could have been a rout by halftime. But the Broncos personified the bend-don’t-break ideal, making timely stops in the final third of the field. Houston was held to field goals of 29, 38 and 38 yards while Denver’s offense could do nothing but punt. The second of those field goals built the lead to its largest margin: only 13-0 despite total yards favoring the Texans 194-23 at that point early in the second quarter.Stroud to Collins: As much as the Broncos’ defense deserved credit for keeping them in the game, the one thing they couldn’t contain was Houston’s young quarterback-receiver connection. Nico Collins compiled 191 receiving yards on nine catches including the decisive touchdown from C.J. Stroud early in the fourth. They also connected for a pair of 50-yard receptions.Wilson’s down...